Repurposing antihypertensive drugs for pain disorders: a drug-target mendelian randomization study
The findings indicate that antihypertensive medications may exert varied effects on pain management, suggesting a repurposing potential for treating specific pain disorders. The results advocate for further research to confirm these associations and to explore underlying mechanisms, to optimize pain management practices.
Authors
- Ao Li (ORCID: https://orcid.org/0000-0001-7983-7062)
- Chenyu Zhang (ORCID: https://orcid.org/0000-0001-8937-1155)
- Ping Chen (ORCID: https://orcid.org/0000-0003-0295-0846)
- Shu-Ming Li (ORCID: https://orcid.org/0000-0002-7460-1349)
- Kai Du (ORCID: https://orcid.org/0009-0004-8375-869X)
Institutions
- Beijing University of Chinese Medicine (CN)
- Capital Medical University (CN)
- Beijing Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-08-29
- DOI
- https://doi.org/10.3389/fphar.2024.1448319
- Citations
- 6
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.96