Prognosis in HR-positive metastatic breast cancer with HER2-low versus HER2-zero treated with CDK4/6 inhibitor and endocrine therapy: a meta-analysis

These results indicated that HER2-low status did not have a significant association with ORR and OS, but it may have a worse impact on PFS in patients who received mixed-line or first-line CDK4/6i and ET, as well as mixed-line or post-line palbociclib plus ET.

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Publication Details

Journal
Frontiers in Oncology
Published
2024-08-29
DOI
https://doi.org/10.3389/fonc.2024.1413674
Citations
7
Primary Topic
Advanced Breast Cancer Therapies
Type
article
Field-Weighted Citation Impact
2.93
Controls
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article

Prognosis in HR-positive metastatic breast cancer with HER2-low versus HER2-zero treated with CDK4/6 inhibitor and endocrine therapy: a meta-analysis

Wei-Yun Xu, Lin-Yu Xia, Qing-Lin Hu, Xuchen Cao
7 citations
Frontiers in Oncology
Advanced Breast Cancer Therapies
2.93
article

Prognosis in HR-positive metastatic breast cancer with HER2-low versus HER2-zero treated with CDK4/6 inhibitor and endocrine therapy: a meta-analysis

Wei-Yun Xu, Lin-Yu Xia, Qing-Lin Hu, Xuchen Cao
article en
7 citations

Abstract

These results indicated that HER2-low status did not have a significant association with ORR and OS, but it may have a worse impact on PFS in patients who received mixed-line or first-line CDK4/6i and ET, as well as mixed-line or post-line palbociclib plus ET.

Frontiers in OncologyVol. 14
Tianjin Medical University Cancer Institute and Hospital (CN), Mianyang Central Hospital (CN), First Affiliated Hospital of Chengdu Medical College (CN)
Good health and well-being
Openalex Percentile: Top 8%
Advanced Breast Cancer Therapies
2.93
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