Analysis of antiparasitic activity of wild plants of Eastern and Northern Kazakhstan

Various helminthoses and other parasitic infections are widespread among farm animals. Helminthic infections are typically treated with anthelmintic drugs; however, resistance to these drugs is becoming an increasingly serious problem. Investigating potential herbal antiparasitic agents, which are inexpensive and widely available, could be a promising alternative. Anthelmintic properties have been identified in oil, hydroalcoholic, and most aqueous extracts of Filipendula vulgaris Moench., Pinus sylvestris, Picea abies L., Abies sibirica, Pinus sibirica DuTour, Juniperus communis L., and Paeonia anomala L. from forest ecosystems in Eastern Kazakhstan, as well as in Ferula tatarica Fisch., Pulsatilla uralensis (Zămels) Tzvel., and Serratula coronata L. from ecosystems in Northern Kazakhstan. The greatest impact and fastest death of annelids were observed with alcohol tinctures, while aqueous extracts had the least effect. The best anthelmintic properties were found in the aqueous-alcoholic extracts of the underground part of Pulsatilla uralensis (Zămels) Tzvel. and the alcohol tincture of the aboveground part of Serratula coronata L. For the first time, the antiparasitic activity of both the aboveground and underground parts of Pulsatilla uralensis (Zămels) Tzvel., growing in Northern Kazakhstan, has been described.