Development and characterization of a preclinical mouse model of alkali-induced limbal stem cell deficiency
We developed and comprehensively characterized a preclinical mouse model of alkali-induced LSCD. Understanding the pathophysiological processes that transpire on the ocular surface in LSCD is key to discovering, testing, and advancing biological and pharmacological interventions that can be dispensed prior to or in conjunction with stem cell therapy to rehabilitate the cornea and restore vision.
Authors
- Lina Sprogyte
- Nick Di Girolamo (ORCID: https://orcid.org/0000-0002-0020-5730)
- Nicodemus Tedla (ORCID: https://orcid.org/0000-0002-8226-8064)
- Alexander Richardson (ORCID: https://orcid.org/0000-0001-7521-655X)
- Lamia Nureen
- Mijeong Park (ORCID: https://orcid.org/0000-0003-1872-0412)
Institutions
- UNSW Sydney (AU)
Publication Details
- Journal
- The Ocular Surface
- Published
- 2024-08-29
- DOI
- https://doi.org/10.1016/j.jtos.2024.08.015
- Citations
- 11
- Primary Topic
- Corneal Surgery and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.45
Funders
- U.S. Department of Defense
- National Health and Medical Research Council