FPS-ZM1 attenuates the deposition of lipid in the liver of diabetic mice by sterol regulatory element binding protein-1c
Generally, FPS-ZM1 may attenuate lipid deposition in hepatocytes of diabetic mice via SREBP-1c down-regulation. This may depend on the downregulation of p65 nfκb and p38 MAPK phosphorylation.
Authors
- Wanwan Zhao
- Zhen Zhang (ORCID: https://orcid.org/0000-0002-0804-8741)
- Mengting He (ORCID: https://orcid.org/0000-0001-8773-3167)
- Ya Zhang (ORCID: https://orcid.org/0000-0002-7330-3884)
- Haoqiang Zhang (ORCID: https://orcid.org/0000-0002-2417-7906)
- Bing Song (ORCID: https://orcid.org/0000-0001-7750-4635)
- Jinlei Liu (ORCID: https://orcid.org/0000-0002-7581-3941)
- Mengshu Zhang (ORCID: https://orcid.org/0000-0002-7496-1811)
Institutions
- University of Science and Technology of China (CN)
- Affiliated Hospital of Jining Medical University (CN)
- Jinzhou Medical University (CN)
Publication Details
- Journal
- BMC Endocrine Disorders
- Published
- 2024-08-29
- DOI
- https://doi.org/10.1186/s12902-024-01705-2
- Citations
- 5
- Primary Topic
- Cholesterol and Lipid Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 2.86
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Department of Education of Liaoning Province
- University of Science and Technology of China