GP VI–Mediated Platelet Activation and Procoagulant Activity Aggravate Inflammation and Aortic Wall Remodeling in Abdominal Aortic Aneurysm
In conclusion, our results emphasize the potential need for a GP VI-targeted antiplatelet therapy to reduce AAA initiation and progression, as well as to protect patients with AAA from aortic rupture.
Authors
- Margitta Elvers
- Joscha Mulorz
- Götz Münch (ORCID: https://orcid.org/0000-0002-5552-4923)
- Silvia Goebel
- Maria Grandoch (ORCID: https://orcid.org/0000-0002-4382-1947)
- Kim Jürgen Krott (ORCID: https://orcid.org/0009-0009-0391-2068)
- Evelyn Krüger
- Madhumita Chatterjee (ORCID: https://orcid.org/0000-0002-3428-4107)
- Niloofar Salehzadeh
- Tobias Feige
- Hubert Schelzig
- Wiebke Ibing
- A Bosbach
- J Ortscheid (ORCID: https://orcid.org/0009-0002-9531-1102)
- Markus U. Wagenhäuser (ORCID: https://orcid.org/0000-0002-2936-0689)
- Irena Krüger
Institutions
- Düsseldorf University Hospital (DE)
- STZ eyetrial (DE)
- advanceCOR (Germany) (DE)
- Heinrich Heine University Düsseldorf (DE)
- University of Tübingen (DE)
Publication Details
- Journal
- Arteriosclerosis Thrombosis and Vascular Biology
- Published
- 2024-08-29
- DOI
- https://doi.org/10.1161/atvbaha.123.320615
- Citations
- 22
- Primary Topic
- Antiplatelet Therapy and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 8.84