Fance deficiency impaired DNA damage repair of prospermatogonia and altered the repair dynamics of spermatocytes
Fance deficiency caused massive male germ cell loss involved in the imbalance of DNA damage repair in prospermatogonia and altered dynamics of proteins in homologous recombination, DNA end resection, and crossover, providing new insights into the etiology and molecular basis of NOA.
Authors
- Huan Yin (ORCID: https://orcid.org/0000-0001-8755-3350)
- Chun Fu (ORCID: https://orcid.org/0000-0002-1413-0864)
- Zhixian Zhou
Institutions
- Central South University (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- Reproductive Biology and Endocrinology
- Published
- 2024-08-29
- DOI
- https://doi.org/10.1186/s12958-024-01284-w
- Citations
- 2
- Primary Topic
- Sperm and Testicular Function
- Type
- article
- Field-Weighted Citation Impact
- 1.07