The Synergistic Inhibitory Effect of Combination Drug Treatment of Enteromorpha Prolifera Polysaccaharide and Doxorubicin Hydrochloride on A549 Cell
The combination of EPP and DOX can block cell cycle, inhibit cell mitochondrial function, promote cell apoptosis, and enhance the killing ability of DOX on tumor cells. This study supports the antitumor activity of enterococcus acid polysaccharide and provides insights on reducing doxorubicin toxicity and drug resistance. It holds great significance for applying traditional Chinese natural medicine in clinical disease treatment.
Authors
- Yingying Huang (ORCID: https://orcid.org/0000-0002-5035-2739)
- Li Liu (ORCID: https://orcid.org/0000-0001-8986-8073)
- Chun Guo (ORCID: https://orcid.org/0000-0002-1540-3166)
- Yueting Xing
- Nan Zhou (ORCID: https://orcid.org/0000-0003-0739-9838)
- Wei Yin
- Jiajia Wang (ORCID: https://orcid.org/0009-0005-2547-9059)
- Yanwei Li (ORCID: https://orcid.org/0000-0002-6837-6421)
Institutions
- Zhejiang University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2024-08-21
- DOI
- https://doi.org/10.31083/j.fbl2908300
- Citations
- 2
- Primary Topic
- Seaweed-derived Bioactive Compounds
- Type
- article
- Field-Weighted Citation Impact
- 1.20