Revealing Cellular Heterogeneity and Key Regulatory Factors of Triple-Negative Breast Cancer through Single-Cell RNA Sequencing
The four epithelial cell subsets and two critical regulons identified based on the scRNA-seq data could help explore the underlying intratumoral heterogeneity molecular mechanism and develop effective therapies for TNBC.
Authors
- Hu Zhang (ORCID: https://orcid.org/0000-0003-0868-952X)
- Xinna Du (ORCID: https://orcid.org/0000-0002-8536-246X)
- Yanan Sun (ORCID: https://orcid.org/0009-0002-8366-7291)
Institutions
- Jiangsu Vocational College of Medicine (CN)
- Beijing Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2024-08-19
- DOI
- https://doi.org/10.31083/j.fbl2908290
- Citations
- 6
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 1.40