Downregulation of SSR2 Enhances Hepatocellular Carcinoma Cisplatin Sensitivity via the Hippo Pathway
Our study shows that SSR2 is important in HCC progression via the Hippo pathway. Thus, targeting the SSR2/Hippo axis might be a potential strategy for overcoming HCC resistance to DDP.
Authors
- Binhui Xie (ORCID: https://orcid.org/0000-0002-7324-9777)
- Honghui Zhang (ORCID: https://orcid.org/0000-0003-4612-4773)
- Xiansen Zhu (ORCID: https://orcid.org/0000-0001-5523-0899)
- Rong Ye (ORCID: https://orcid.org/0000-0002-7897-6009)
- Cuifu Fang (ORCID: https://orcid.org/0000-0001-8495-1900)
- Heping Li (ORCID: https://orcid.org/0000-0002-4281-2475)
- Yilong Ge
- Yuansheng Xiao (ORCID: https://orcid.org/0009-0004-7920-1522)
- Ling Yin (ORCID: https://orcid.org/0009-0002-6790-0006)
- Qingquan Liu (ORCID: https://orcid.org/0000-0002-5977-0785)
Institutions
- Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- First Affiliated Hospital of Gannan Medical University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2024-08-21
- DOI
- https://doi.org/10.31083/j.fbl2908299
- Citations
- 5
- Primary Topic
- Hippo pathway signaling and YAP/TAZ
- Type
- article
- Field-Weighted Citation Impact
- 1.63
Funders
- National Natural Science Foundation of China
- Sun Yat-sen University
- Natural Science Foundation of Jiangxi Province
- Education Department of Jiangxi Province