A retrospective analysis of clinical characteristics and outcomes of pediatric fulminant myocarditis

Severe myocardial injury (AST > 194.00 U/L, LDH > 637.50 U/L, MYO > 265.75 µg/L, BNP > 1738.50 ng/L), acidosis (PH < 7.29, HCO<sub>3</sub><sup>-</sup> <18.45 mmol/L, Lac > 12.30 mmol/L), hypoxia (SpO<sub>2</sub> < 97.50%), inflammatory response (WBC > 9.69*10<sup>9</sup>/L), left ventricular systolic dysfunction (LVEF < 28.25%), multi-organ failure, and respiratory failure are significantly associated with higher mortality rates. These factors can accurately identify AFM children at an increased risk of death.

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Publication Details

Journal
BMC Pediatrics
Published
2024-08-29
DOI
https://doi.org/10.1186/s12887-024-05022-4
Citations
13
Primary Topic
Viral Infections and Immunology Research
Type
article
Field-Weighted Citation Impact
5.23
Controls
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article

A retrospective analysis of clinical characteristics and outcomes of pediatric fulminant myocarditis

Yang Xu, Min Da, Xun Yang, Yuhang Zhao et al.
13 citations
BMC Pediatrics
Viral Infections and Immunology Research
5.23
article

A retrospective analysis of clinical characteristics and outcomes of pediatric fulminant myocarditis

Yang Xu, Min Da, Xun Yang, Yuhang Zhao, Jirong Qi
article en
13 citations

Abstract

Severe myocardial injury (AST > 194.00 U/L, LDH > 637.50 U/L, MYO > 265.75 µg/L, BNP > 1738.50 ng/L), acidosis (PH < 7.29, HCO<sub>3</sub><sup>-</sup> <18.45 mmol/L, Lac > 12.30 mmol/L), hypoxia (SpO<sub>2</sub> < 97.50%), inflammatory response (WBC > 9.69*10<sup>9</sup>/L), left ventricular systolic dysfunction (LVEF < 28.25%), multi-organ failure, and respiratory failure are significantly associated with higher mortality rates. These factors can accurately identify AFM children at an increased risk of death.

BMC PediatricsVol. 24(1)
Nanjing Children's Hospital (CN), Second Affiliated Hospital of Nanjing Medical University (CN), Nanjing Medical University (CN)
Openalex Percentile: Top 4%
Viral Infections and Immunology Research
5.23
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