Genetic Variants can Predict the Outcome of Brace Treatment in Patients With Adolescent Idiopathic Scoliosis

SNP rs10738445 were significantly associated with brace treatment effectiveness. The other four SNPs were not significantly associated with the outcome of bracing. More SNPs and predictors should be included in future study to develop a more accurate predictive model for clinical application.

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Publication Details

Journal
Spine
Published
2024-08-29
DOI
https://doi.org/10.1097/brs.0000000000005137
Primary Topic
Scoliosis diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Genetic Variants can Predict the Outcome of Brace Treatment in Patients With Adolescent Idiopathic Scoliosis

Zhenhua Feng, Yongrong Qiu, Kaixing Min, Zhichong Wu et al.
Spine
Scoliosis diagnosis and treatment
article

Genetic Variants can Predict the Outcome of Brace Treatment in Patients With Adolescent Idiopathic Scoliosis

Zhenhua Feng, Yongrong Qiu, Kaixing Min, Zhichong Wu, Leilei Xu, Zhicheng Dai, Zezhang Zhu
article en

Abstract

SNP rs10738445 were significantly associated with brace treatment effectiveness. The other four SNPs were not significantly associated with the outcome of bracing. More SNPs and predictors should be included in future study to develop a more accurate predictive model for clinical application.

SpineVol. 50(4)
Nanjing Drum Tower Hospital (CN)
Good health and well-being
Openalex Percentile: Top 74%
Scoliosis diagnosis and treatment
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