Methylation-Associated Nucleosomal Patterns of Cell-Free DNA in Cancer Patients and Pregnant Women

CpG-associated cfDNA nucleosomal patterns of cfDNA molecules are influenced by DNA methylation and might be useful for biomarker developments for cancer liquid biopsy and noninvasive prenatal testing.

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Publication Details

Journal
Clinical Chemistry
Published
2024-08-29
DOI
https://doi.org/10.1093/clinchem/hvae118
Citations
8
Primary Topic
Prenatal Screening and Diagnostics
Type
article
Field-Weighted Citation Impact
8.87
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article

Methylation-Associated Nucleosomal Patterns of Cell-Free DNA in Cancer Patients and Pregnant Women

L Y Lois Choy, John Wong, Tak Yeung Leung, Guannan Kang et al.
8 citations
Clinical Chemistry
Prenatal Screening and Diagnostics
8.87
article

Methylation-Associated Nucleosomal Patterns of Cell-Free DNA in Cancer Patients and Pregnant Women

L Y Lois Choy, John Wong, Tak Yeung Leung, Guannan Kang, Qing Zhou, Stephanie C Y Yu, Jinyue Bai, Stephen L. Chan, L Mary-Jane, Wenlei Peng, So Ling Lau, Rong Qiao, Spencer C Ding, K.C. Allen Chan, W.K. Lam, Peiyong Jiang, Guanhua Zhu, Chian Xi Shirley Deng, Xingqian Li, Y M Dennis Lo
article en
8 citations

Abstract

CpG-associated cfDNA nucleosomal patterns of cfDNA molecules are influenced by DNA methylation and might be useful for biomarker developments for cancer liquid biopsy and noninvasive prenatal testing.

Clinical ChemistryVol. 70(11)
Chinese University of Hong Kong (HK), Hong Kong Science and Technology Parks Corporation (HK), Prince of Wales Hospital (CN)
Good health and well-being
Openalex Percentile: Top 2%
Prenatal Screening and Diagnostics
8.87
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