Potential carcinogenic role of Reg IV in ulcerative colitis-associated colorectal neoplasia
Higher expression of Reg IV in patients with UC-dysplasia and UC-CRC versus KRAS and P53 expression in sporadic CRC, suggests a potential role of Reg IV in UC carcinogenesis pathway. This could advocate the use of Reg IV as a screening biomarker for UC-N among patients with long-standing UC as well as a promising targeted therapeutic strategy.
Authors
- Tamer Haydara (ORCID: https://orcid.org/0000-0003-3385-4582)
- Yosra Abdelmonem Zamzam (ORCID: https://orcid.org/0000-0002-2391-5890)
- Ayman Mohamed Elsaka (ORCID: https://orcid.org/0000-0002-5873-0917)
- Yomna Zamzam (ORCID: https://orcid.org/0000-0003-0270-3140)
- Lamiaa Al Fadaly
- Alaa Ibraheem Amer
Institutions
- Tanta University (EG)
Publication Details
- Journal
- ecancermedicalscience
- Published
- 2024-08-29
- DOI
- https://doi.org/10.3332/ecancer.2024.1751
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00