Inhibition of CXCR2 as a therapeutic target for chronic post-surgical pain: Insights from animal and cell models
This study indicated that the high expression of CXCR2 activates the JAK1/STAT3 signaling pathway, enhances EPAC1 activation in microglial cells, and exacerbates CPSP.
Authors
- Zhusheng Chen (ORCID: https://orcid.org/0000-0002-0315-7359)
- Can Zhou (ORCID: https://orcid.org/0000-0003-3885-9702)
- Yang� Yang (ORCID: https://orcid.org/0000-0003-1222-1209)
- Jiacheng Zhao (ORCID: https://orcid.org/0009-0009-8459-6799)
- Yongtao Gao (ORCID: https://orcid.org/0000-0002-9436-7393)
- Chenlu Jian
- Jiapei Cai
- Ming Li (ORCID: https://orcid.org/0009-0002-3553-6932)
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
Publication Details
- Journal
- CytoJournal
- Published
- 2024-08-29
- DOI
- https://doi.org/10.25259/cytojournal_46_2024
- Citations
- 2
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.65
Funders
- Government of Jiangsu Province