Common molecular and pathophysiological underpinnings of delirium and Alzheimer’s disease: molecular signatures and therapeutic indications
The study outlined the common key biomolecules and biological pathways shared by delirium and AD. The computationally reported potential drug molecules need a deeper investigation including clinical trials to validate their effectiveness. The outcomes from this study will help to understand the typical pathophysiological relationship between delirium and AD and flag future therapeutic development research for delirium.
Authors
- Jeff Gow (ORCID: https://orcid.org/0000-0002-5726-298X)
- Md. Nurul Haque Mollah (ORCID: https://orcid.org/0000-0002-3883-3396)
- Md. Parvez Mosharaf
- Rashidul Alam Mahumud (ORCID: https://orcid.org/0000-0001-9788-1868)
- Khorshed Alam (ORCID: https://orcid.org/0000-0003-2232-0745)
Institutions
- New South Wales Department of Health (AU)
- University of Southern Queensland (AU)
- University of Rajshahi (BD)
- University of KwaZulu-Natal (ZA)
Publication Details
- Journal
- BMC Geriatrics
- Published
- 2024-08-29
- DOI
- https://doi.org/10.1186/s12877-024-05289-3
- Citations
- 13
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 5.48
Funders
- Australian Government
- University of Southern Queensland