Exploring the molecular mechanisms of macrophages in islet transplantation using single-cell analysis

This study significantly advances the understanding of macrophage roles within the context of islet transplantation by revealing the interactions between immune pathways and cellular fate processes. The findings highlight potential therapeutic targets for enhancing graft survival and function, emphasizing the importance of understanding the immunological aspects of transplant acceptance and longevity.

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Publication Details

Journal
Frontiers in Immunology
Published
2024-08-29
DOI
https://doi.org/10.3389/fimmu.2024.1407118
Citations
7
Primary Topic
Pancreatic function and diabetes
Type
article
Field-Weighted Citation Impact
4.01
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article

Exploring the molecular mechanisms of macrophages in islet transplantation using single-cell analysis

Shujuan Chen, Lisha Mou, Zhiming Cai, Zuhui Pu et al.
7 citations
Frontiers in Immunology
Pancreatic function and diabetes
4.01
article

Exploring the molecular mechanisms of macrophages in islet transplantation using single-cell analysis

Shujuan Chen, Lisha Mou, Zhiming Cai, Zuhui Pu, Ying Lü, Zijing Wu
article en
7 citations

Abstract

This study significantly advances the understanding of macrophage roles within the context of islet transplantation by revealing the interactions between immune pathways and cellular fate processes. The findings highlight potential therapeutic targets for enhancing graft survival and function, emphasizing the importance of understanding the immunological aspects of transplant acceptance and longevity.

Frontiers in ImmunologyVol. 15
BGI Group (China) (CN), Shenzhen Institutes of Advanced Technology (CN), Shenzhen Second People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 6%
Pancreatic function and diabetes
4.01
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