Prognostic significance and treatment strategies for IKZF1 deletion in pediatric B-cell precursor acute lymphoblastic leukemia
The prognostic effect of IKZF1<sup>del</sup> may vary in different protocols. Compared with higher intensity chemotherapy, the MRD-guided protocol may be a more effective approach to treating BCP-ALL with IKZF1<sup>del</sup> in children.
Authors
- Shuquan Zhuang
- Kai-Zhi Weng
- Lili Pan (ORCID: https://orcid.org/0000-0001-6326-3260)
- Yiqiao Chen (ORCID: https://orcid.org/0000-0003-3575-5553)
- Nainong Li (ORCID: https://orcid.org/0000-0001-5620-5791)
- Shuxian Huang (ORCID: https://orcid.org/0000-0002-3476-4389)
- Biyun Guo
- Zhulan Lian
- Yongzhi Zheng
- Xiaofang Wang
Institutions
- Fujian Medical University (CN)
- First Affiliated Hospital of Xiamen University (CN)
- Zhangzhou Municipal Hospital of Fujian Province (CN)
- Union Hospital (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-08-29
- DOI
- https://doi.org/10.1186/s12885-024-12828-z
- Citations
- 4
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 2.17
Funders
- National Key Clinical Specialty Discipline Construction Program of China