Elevated nuclear expression of ZHX1 correlates with poor prognosis in hepatocellular carcinoma (HCC): Comparison of nuclear and cytoplasmic distribution of the ZHX family in HCC cells

These results suggest that the expression and localization of different ZHXs may be related to HCC progression, potentially inferring genetic backgrounds such as TERT promoter mutation. Further studies on the relationship between HCC and ZHXs will enhance our understanding and control of HCC.

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Publication Details

Journal
Hepatology Research
Published
2024-08-29
DOI
https://doi.org/10.1111/hepr.14100
Primary Topic
Cancer-related gene regulation
Type
article
Field-Weighted Citation Impact
0.00

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article

Elevated nuclear expression of ZHX1 correlates with poor prognosis in hepatocellular carcinoma (HCC): Comparison of nuclear and cytoplasmic distribution of the ZHX family in HCC cells

Hitomi Takada, Shinya Maekawa, Shinichi Takano, Shinya Takaoka et al.
Hepatology Research
Cancer-related gene regulation
article

Elevated nuclear expression of ZHX1 correlates with poor prognosis in hepatocellular carcinoma (HCC): Comparison of nuclear and cytoplasmic distribution of the ZHX family in HCC cells

Hitomi Takada, Shinya Maekawa, Shinichi Takano, Shinya Takaoka, Tatsuya Yamaguchi, Jianglin Fan, Yuhong Ma, Yasuyuki Komiyama, Masaru Muraoka, Yuichiro Suzuki, Takeshi Ishida, Nobuyuki Enomoto, Mitsuaki Sato
article en

Abstract

These results suggest that the expression and localization of different ZHXs may be related to HCC progression, potentially inferring genetic backgrounds such as TERT promoter mutation. Further studies on the relationship between HCC and ZHXs will enhance our understanding and control of HCC.

Hepatology ResearchVol. 55(1)
Ningxia Medical University (CN), Wuyi University (CN), The Fourth People's Hospital of Ningxia Hui Autonomous Region (CN), University of Yamanashi (JP)
Japan Agency for Medical Research and Development, Japan Society for the Promotion of Science
Good health and well-being
Openalex Percentile: Top 87%
Cancer-related gene regulation
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