Does Age Influence Immunosuppressant Drug Pharmacokinetics in Kidney Transplant Recipients?
Differences in MPA were found with advancing age and may be due to altered kidney function, haematocrit, plasma protein binding and/or drug absorption. Future research should explore specific covariate contributions to this further.
Authors
- Brett C McWhinney (ORCID: https://orcid.org/0000-0001-9632-1148)
- Christine E. Staatz (ORCID: https://orcid.org/0000-0002-4595-9376)
- Nicole M. Isbel (ORCID: https://orcid.org/0000-0002-9566-7179)
- Amelia R. Cossart
- Scott B. Campbell (ORCID: https://orcid.org/0000-0003-1338-2151)
Institutions
- Queensland Health (AU)
- The University of Queensland (AU)
- Princess Alexandra Hospital (AU)
Publication Details
- Journal
- European Journal of Drug Metabolism and Pharmacokinetics
- Published
- 2024-08-29
- DOI
- https://doi.org/10.1007/s13318-024-00914-3
- Citations
- 2
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.02
Funders
- Metro South Health
- University of Queensland