Picroside II suppresses chondrocyte pyroptosis through MAPK/NF-κB/NLRP3 signaling pathway alleviates osteoarthritis
Our research suggests that Picroside II can inhibit chondrocyte pyroptosis and ameliorate osteoarthritis progression by modulating the MAPK/NF-κB signaling pathway.
Authors
- Shaocong Li
- Fanchen Wang
- Zhaofeng Pan (ORCID: https://orcid.org/0000-0003-3478-8855)
- Jiacong Xiao
- Miao Li (ORCID: https://orcid.org/0000-0001-6672-8692)
- Xintian Wang
- Chi Zhou (ORCID: https://orcid.org/0000-0003-1905-9494)
- Qi He
- Haibin Wang
Institutions
- Guangzhou University of Chinese Medicine (CN)
- First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-08-29
- DOI
- https://doi.org/10.1371/journal.pone.0308731
- Citations
- 5
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- National Natural Science Foundation of China
- Guangzhou Municipal Science and Technology Project