Functional Polymorphisms Regulate <i>FOXO1</i> Transcript Expression and Contribute to the Risk and Symptom Severity of HDM-Induced Allergic Rhinitis
FOXO1 transcript expression in PBMC has a strong association with the risk and symptom severity of AR. Genetic variants tagged by rs9549246 were shown to affect the expression of FOXO1 and contribute to the development of AR in the SMCSGES population.
Authors
- Yee‐How Say (ORCID: https://orcid.org/0000-0003-2363-5239)
- Kavita Reginald (ORCID: https://orcid.org/0000-0003-1530-5934)
- Terence Yin Weng Lam (ORCID: https://orcid.org/0000-0003-2991-8969)
- Fook Tim Chew (ORCID: https://orcid.org/0000-0003-1337-5146)
- Yang Yie Sio (ORCID: https://orcid.org/0000-0002-3549-1706)
- Kefan Du
Institutions
- National University of Singapore (SG)
- Sunway University (MY)
- Universiti Tunku Abdul Rahman (MY)
Publication Details
- Journal
- International Archives of Allergy and Immunology
- Published
- 2024-08-29
- DOI
- https://doi.org/10.1159/000540686
- Citations
- 4
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.31