Trisomy 8 presentation by inflammatory manifestations and its response to thalidomide: two case reports and narrative review
The early clinical manifestations of T8 in children lack specificity, and the diagnosis is mainly based on karyotype analysis, gastrointestinal endoscopy and bone marrow aspiration findings. Active and effective immunoregulatory therapy and long-term follow-up can improve the prognosis of patients with T8.
Authors
- Zhidan Fan (ORCID: https://orcid.org/0009-0008-2473-2480)
- Yan Zhao (ORCID: https://orcid.org/0000-0002-5181-0367)
- Haiguo Yu (ORCID: https://orcid.org/0000-0001-8255-9390)
- Xiaohua Zhang (ORCID: https://orcid.org/0000-0001-5053-3161)
- Jing Jin (ORCID: https://orcid.org/0000-0002-1866-8653)
- Yuting Pan (ORCID: https://orcid.org/0009-0002-0920-5865)
Institutions
- Second Affiliated Hospital of Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2024-08-20
- DOI
- https://doi.org/10.3389/fped.2024.1431511
- Citations
- 2
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.91
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China