Thrombophilia as a reason for the development of ischemic stroke at young age. Features of the clinic and diagnosis

Introduction . Thrombophilia is a common cause of neurological complications. Aim . to present a clinical observation of the development of ischemic stroke in a patient with hereditary thrombophilia. Main findings . A case is presented of a man, aged 30, who developed an ischemic stroke in the basin of the left medial artery. A diagnostic study revealed that the development of the ischemic stroke was facilitated by thrombophilia caused by a combination of polymorphic variants of the fibrinogen genes (G-455A(G-467A)) and methylenetetrahydrofolate reductase (C677T). Thus, hereditary thrombophilia was a risk factor for the development of ischemic stroke in the patient at a young age. Therefore, in the absence of traditional risk factors for the development of ischemic stroke, a genetic analysis for thrombophilia is necessary.