Predictive value of combining urinary N-acetyl-β-D-glucosaminidase and serum homocysteine for contrast-induced nephropathy in patients after percutaneous coronary intervention
The uNAG and sHCY panel demonstrated better sensitivity and specificity for predicting the diagnosis and prognosis of CIN in patients after PCI, earlier than sCr. The combination of these biomarkers revealed a significantly superior discriminative performance for CIN detection and prognosis compared to using uNAG or sHCY alone.
Authors
- Jie Yang (ORCID: https://orcid.org/0000-0002-8393-3580)
- Hongying Cao (ORCID: https://orcid.org/0000-0001-6207-0168)
- Dongling Huang (ORCID: https://orcid.org/0000-0003-1587-6825)
- Wanxia Wei
- Zhengzhuang Huang
- Changjun Luo
- Jincheng Li (ORCID: https://orcid.org/0000-0002-8363-3916)
- Xueling Lu (ORCID: https://orcid.org/0009-0004-3492-0419)
- Yiling Zhai (ORCID: https://orcid.org/0000-0002-7828-8898)
- Zhou Huang (ORCID: https://orcid.org/0000-0001-9385-0597)
- Chunyang Dong
- Nianying Qin
- Fan Wang (ORCID: https://orcid.org/0000-0002-2245-3671)
- Wei J. Wang (ORCID: https://orcid.org/0000-0002-4848-7394)
Institutions
- Guangxi University (CN)
- Guangxi Medical University (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
- Fourth Affiliated Hospital of Guangxi Medical University (CN)
- First People's Hospital of Nanning (CN)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2024-08-20
- DOI
- https://doi.org/10.3389/fcvm.2024.1423836
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Guangxi Medical University
- Youth Science Foundation of Guangxi Medical University