A single intravenous reelin injection restores corticosterone-induced neurochemical and behavioral alterations in dams during the post-partum period
This study brings new insights into the putative antidepressant-like effect of peripherally administered reelin in an animal model of PPD. Future studies should be conducted to investigate these effects on a dose-response paradigm and to further elucidate the mechanisms underlying the antidepressant-like effects of reelin.
Authors
- Lisa E. Kalynchuk (ORCID: https://orcid.org/0000-0003-0079-275X)
- Carla L. Sánchez-Lafuente (ORCID: https://orcid.org/0000-0003-2046-3574)
- Brady S. Reive (ORCID: https://orcid.org/0000-0001-5208-6051)
- Héctor J. Caruncho (ORCID: https://orcid.org/0000-0003-4614-9495)
- Kaylene Scheil
- Ciara S. Halvorson (ORCID: https://orcid.org/0009-0006-5922-7551)
- Jenessa N. Johnston (ORCID: https://orcid.org/0000-0003-2986-3179)
- Mariana Jimenez
- Darian Colpitts
Institutions
- University of Victoria (CA)
Publication Details
- Journal
- Frontiers in Molecular Neuroscience
- Published
- 2024-08-20
- DOI
- https://doi.org/10.3389/fnmol.2024.1442332
- Citations
- 3
- Primary Topic
- Neuroendocrine regulation and behavior
- Type
- article
- Field-Weighted Citation Impact
- 1.93
Funders
- Canadian Institutes of Health Research
- Natural Sciences and Engineering Research Council of Canada