Efficacy and Safety of Oral Neomycin for the Decolonization of Carbapenem-Resistant Enterobacterales: An Open-Label Randomized Controlled Trial

Neomycin effectively reduced CRE colonization on day 7 ± 2, but its impact waned by day 14 ± 2. This suggests that neomycin dosage was too low and the duration of treatment was too short for lasting CRE decolonization.

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Publication Details

Journal
Antibiotics
Published
2024-08-20
DOI
https://doi.org/10.3390/antibiotics13080781
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy and Safety of Oral Neomycin for the Decolonization of Carbapenem-Resistant Enterobacterales: An Open-Label Randomized Controlled Trial

Ananya Srisomnuek, Lalita Tancharoen, Surapee Tiengrim, Narisara Thamthaweechok et al.
Antibiotics
Antibiotic Resistance in Bacteria
article

Efficacy and Safety of Oral Neomycin for the Decolonization of Carbapenem-Resistant Enterobacterales: An Open-Label Randomized Controlled Trial

Ananya Srisomnuek, Lalita Tancharoen, Surapee Tiengrim, Narisara Thamthaweechok, Visanu Thamlikitkul, Teerawit Tangkorskul
article en

Abstract

Neomycin effectively reduced CRE colonization on day 7 ± 2, but its impact waned by day 14 ± 2. This suggests that neomycin dosage was too low and the duration of treatment was too short for lasting CRE decolonization.

AntibioticsVol. 13(8)
Siriraj Hospital (TH), Mahidol University (TH)
Good health and well-being
Openalex Percentile: Top 91%
Antibiotic Resistance in Bacteria
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