Brazil nut (Bertholletia excelsa) and metformin abrogate cardiac complication in fructose/STZ-induced type 2 diabetic rats by attenuating oxidative stress and modulating the MAPK-mTOR/NFkB/IL-10 signaling pathways
This study shows that Brazil nut contains several bioactive compounds that support its biological properties as well as its candidature as a complementary therapy to metformin in mitigating cardiac complications arising from DM in rats.
Authors
- Zhenzuo Li (ORCID: https://orcid.org/0000-0003-3668-606X)
- Dongfang Bai (ORCID: https://orcid.org/0000-0002-9610-2786)
- Li Zhang (ORCID: https://orcid.org/0000-0002-3617-2627)
- Baolan Wang (ORCID: https://orcid.org/0000-0003-0491-8591)
Institutions
- The Fourth People's Hospital (CN)
- Fourth People’s Hospital of Jinan (CN)
- Taian City Central Hospital (CN)
Publication Details
- Journal
- Food & Nutrition Research
- Published
- 2024-08-20
- DOI
- https://doi.org/10.29219/fnr.v68.10749
- Citations
- 3
- Primary Topic
- Diet, Metabolism, and Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.07