Simultaneous detection of multiple urinary biomarkers in patients with early-stage diabetic kidney disease using Luminex liquid suspension chip technology
The urinary levels of VDBP, RBP4, KIM-1, and TNFR-2 can be detected simultaneously using Luminex liquid suspension chip technology. The combination of these biomarkers, which reflect different mechanisms of kidney damage, had the highest diagnostic value for DKD. However, this finding should be explored further to understand the synergistic effects of these biomarkers.
Authors
- Jingyu Wang (ORCID: https://orcid.org/0000-0002-8860-5623)
- Baocheng Chang (ORCID: https://orcid.org/0000-0002-4926-2525)
- Yuan Li (ORCID: https://orcid.org/0000-0002-3171-8053)
- Xinran Li (ORCID: https://orcid.org/0000-0001-8988-7223)
- Meng Cheng (ORCID: https://orcid.org/0000-0001-9834-8192)
- Shenglan Wang
- Juhong Yang (ORCID: https://orcid.org/0000-0003-2216-0585)
- Xinxin Zhang (ORCID: https://orcid.org/0000-0003-0297-7061)
Institutions
- Guangdong Medical College (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-08-20
- DOI
- https://doi.org/10.3389/fendo.2024.1443573
- Citations
- 5
- Primary Topic
- Electrochemical sensors and biosensors
- Type
- article
- Field-Weighted Citation Impact
- 1.04
Funders
- National Natural Science Foundation of China
- Tianjin Medical University