GnRH agonist-only trigger, compared to dual trigger, reduces oocyte retrieval rate in high responders without affecting cumulative live birth rate
GnRH agonist-only triggers resulted in a lower oocyte retrieval rate compared to dual triggers but did not significantly affect cumulative LBR in high responders. This approach effectively reduces OHSS risk without compromising pregnancy outcomes, making it a preferable option in freeze-all strategies, despite a longer oocyte pick-up duration and a medium cost. GnRH agonist-only trigger, however, may not be suitable for fresh embryo transfers or patients with low serum LH levels on trigger day.
Authors
- Ya‐Fang Chen (ORCID: https://orcid.org/0000-0003-2995-9189)
- Yu‐Chiao Yi (ORCID: https://orcid.org/0000-0003-3062-6736)
- Shih-Ting Chuan
- Jui‐Chun Chang (ORCID: https://orcid.org/0000-0003-1479-7156)
- Ming-Jer Chen (ORCID: https://orcid.org/0000-0002-5618-1969)
- Hwa-Fen Guu
- Yu Wang (ORCID: https://orcid.org/0000-0002-7046-7971)
- Li-Yu Chen (ORCID: https://orcid.org/0000-0002-1388-1375)
- Hsiao-Fan Kung
Institutions
- National Yang Ming Chiao Tung University (TW)
- Taichung Veterans General Hospital (TW)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-08-20
- DOI
- https://doi.org/10.3389/fendo.2024.1461317
- Citations
- 6
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 3.26