Wearable Perovskite Films for On‐Line Monitoring of Radiotracers in Nuclear Medicine

Abstract On‐line in situ monitoring of radiation emitted by radiotracers during intravenous injection is of crucial importance for the safety of patients and personnel involved in nuclear medicine treatments and analysis. The aim of this work is to assess wearable perovskite ionizing radiation detectors for such application. With this purpose pixelated direct detector based on thin films of 2D layered perovskite PEA 2 PbBr 4 are tested for the monitoring of gamma‐rays emitted by 18 F radiopharmaceutical under different experimental conditions. The wearable detector is here demonstrated being able to detect in real‐time the gamma‐rays emitted by annihilation of 18 F radiotracer. Its reliability is assessed by 18 F half‐life measurement with a maximum accuracy deviation within 8%. The detector also successes in its validation for the foreseen application, demonstrating able to monitor in real‐time the whole injection process and extravasation event.

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Publication Details

Journal
Advanced Materials Technologies
Published
2024-08-20
DOI
https://doi.org/10.1002/admt.202401111
Citations
5
Primary Topic
Perovskite Materials and Applications
Type
article
Field-Weighted Citation Impact
1.04

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article

Wearable Perovskite Films for On‐Line Monitoring of Radiotracers in Nuclear Medicine

Elisa Grassi, Beatrice Fraboni, Matteo Verdi, Laura Basiricò et al.
5 citations
Advanced Materials Technologies
Perovskite Materials and Applications
1.04
article

Wearable Perovskite Films for On‐Line Monitoring of Radiotracers in Nuclear Medicine

Elisa Grassi, Beatrice Fraboni, Matteo Verdi, Laura Basiricò, Valentina Cicero, Andrea Ciavatti, A. Montanari, Mauro Iori, Federica Fioroni, Lorenzo Margotti, Lorenzo Piergallini, N. Tosi
article en
5 citations

Abstract

Abstract On‐line in situ monitoring of radiation emitted by radiotracers during intravenous injection is of crucial importance for the safety of patients and personnel involved in nuclear medicine treatments and analysis. The aim of this work is to assess wearable perovskite ionizing radiation detectors for such application. With this purpose pixelated direct detector based on thin films of 2D layered perovskite PEA 2 PbBr 4 are tested for the monitoring of gamma‐rays emitted by 18 F radiopharmaceutical under different experimental conditions. The wearable detector is here demonstrated being able to detect in real‐time the gamma‐rays emitted by annihilation of 18 F radiotracer. Its reliability is assessed by 18 F half‐life measurement with a maximum accuracy deviation within 8%. The detector also successes in its validation for the foreseen application, demonstrating able to monitor in real‐time the whole injection process and extravasation event.

Advanced Materials TechnologiesVol. 10(2)
Istituto Nazionale di Fisica Nucleare (IT), Azienda Sanitaria Unità Locale di Reggio Emilia (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), University of Bologna (IT)
Ministero della Salute, Università di Bologna, Regione Emilia-Romagna, European Regional Development Fund
Responsible consumption and production
Openalex Percentile: Top 23%
Perovskite Materials and Applications
1.04
DOIOpen Access PDFOpenAlex
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