Unpredictable Cyclosporine Clearance in a Korean Patient With Aplastic Anemia With Adverse Effects: A Case Study

A 29-year-old Korean woman with chronic aplastic anemia presented with seizures due to cyclosporine-induced posterior reversible encephalopathy syndrome, caused by unpredictable oral cyclosporine (CS) accumulation and prolonged elimination. This case demonstrates the need to monitor CS drug levels with careful dose adjustments.

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Publication Details

Journal
Therapeutic Drug Monitoring
Published
2024-08-20
DOI
https://doi.org/10.1097/ftd.0000000000001244
Citations
1
Primary Topic
Pharmacological Effects and Toxicity Studies
Type
article
Field-Weighted Citation Impact
1.11
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article

Unpredictable Cyclosporine Clearance in a Korean Patient With Aplastic Anemia With Adverse Effects: A Case Study

Haim Shmuely, Renata Shihmanter, Edward B. Miller, Ekaterina Shvartsman
1 citations
Therapeutic Drug Monitoring
Pharmacological Effects and Toxicity Studies
1.11
article

Unpredictable Cyclosporine Clearance in a Korean Patient With Aplastic Anemia With Adverse Effects: A Case Study

Haim Shmuely, Renata Shihmanter, Edward B. Miller, Ekaterina Shvartsman
article en
1 citations

Abstract

A 29-year-old Korean woman with chronic aplastic anemia presented with seizures due to cyclosporine-induced posterior reversible encephalopathy syndrome, caused by unpredictable oral cyclosporine (CS) accumulation and prolonged elimination. This case demonstrates the need to monitor CS drug levels with careful dose adjustments.

Therapeutic Drug MonitoringVol. 46(5)
Kaplan Medical Center (IL)
Good health and well-being
Openalex Percentile: Top 18%
Pharmacological Effects and Toxicity Studies
1.11
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