Causal association between serum bilirubin and ischemic stroke: multivariable Mendelian randomization
Our study establishes a causal association between higher genetically determined levels of serum indirect bilirubin and reduced risk of ischemic stroke in an Asian population. Future research should include more in-depth analysis of shared genetic variants between indirect bilirubin and ischemic stroke.
Authors
- Sun Ha Jee (ORCID: https://orcid.org/0000-0001-9519-3068)
- Jong Won Shin (ORCID: https://orcid.org/0009-0003-8587-1445)
- Keum Ji Jung (ORCID: https://orcid.org/0000-0003-4993-0666)
- Mikyung Ryu (ORCID: https://orcid.org/0000-0002-9915-3175)
- Jung-Eun Kim (ORCID: https://orcid.org/0000-0002-5457-745X)
- Heejin Kimm (ORCID: https://orcid.org/0000-0003-4526-0570)
Institutions
- Ulsan College (KR)
- Yonsei University (KR)
- Asan Medical Center (KR)
- University of Ulsan (KR)
- Korea Health Promotion Institute (KR)
- RBio (South Korea) (KR)
- Ajou University (KR)
Publication Details
- Journal
- Epidemiology and Health
- Published
- 2024-08-19
- DOI
- https://doi.org/10.4178/epih.e2024070
- Citations
- 7
- Primary Topic
- Heme Oxygenase-1 and Carbon Monoxide
- Type
- article
- Field-Weighted Citation Impact
- 1.64
Funders
- Korea Health Industry Development Institute