Selective <i>C‐Meth</i>ylenation of <i>N</i>‐Unsubstituted Indoles Using CO<sub>2</sub> Under NaBH<sub>4</sub>/I<sub>2</sub> System
The selective C-methylenation of N-unsubstituted indoles using CO<sub>2</sub> as the C1 source to access diindolylmethane (DIM) and its derivatives is described. This reaction provides a novel method for four-electron reductive functionalization of CO<sub>2</sub> with N-unsubstituted indoles via formation of C-CH<sub>2</sub>-C bonds, and a new access to molecular structures.
Authors
- Zhiqiang Guo (ORCID: https://orcid.org/0000-0001-5444-7455)
- Chanjuan Xi (ORCID: https://orcid.org/0000-0002-9602-7309)
- Jinglong Wu
- Xue-Hong Wei (ORCID: https://orcid.org/0000-0002-3909-7845)
Institutions
- Shanxi University (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- ChemSusChem
- Published
- 2024-08-26
- DOI
- https://doi.org/10.1002/cssc.202401491
- Citations
- 2
- Primary Topic
- Asymmetric Hydrogenation and Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 0.32
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shanxi Province