Long-Term Clinical and Sustained REMIssion in Severe Eosinophilic Asthma Treated With Mepolizumab: The REMI-M Study
This study demonstrates the real-world effectiveness of mepolizumab in achieving clinical remission and sustained remission in severe eosinophilic asthma over 24 months. The identification of distinct factors associated with the likelihood of achieving clinical remission emphasizes the importance of comprehensive management of comorbidities and timely identification of patients who may benefit from biologics.
Authors
- Nunzio Crimi (ORCID: https://orcid.org/0000-0002-8591-4535)
- Nicola Scichilone (ORCID: https://orcid.org/0000-0001-6400-6573)
- Maria D’Amato (ORCID: https://orcid.org/0000-0002-5906-5701)
- Maria Pia Foschino Barbaro (ORCID: https://orcid.org/0000-0001-9939-2697)
- Maria Filomena Caiaffa
- Girolamo Pelaia (ORCID: https://orcid.org/0000-0001-9288-8913)
- Luigi Ciampo (ORCID: https://orcid.org/0009-0005-3024-895X)
- Carolina Vitale (ORCID: https://orcid.org/0000-0002-7392-3610)
- Raffaele Campisi (ORCID: https://orcid.org/0000-0001-9305-6748)
- Giulia Scioscia (ORCID: https://orcid.org/0000-0002-2667-077X)
- Claudia Crimi (ORCID: https://orcid.org/0000-0002-9088-5214)
- Corrado Pelaia (ORCID: https://orcid.org/0000-0002-4236-7367)
- Cecilia Calabrese (ORCID: https://orcid.org/0000-0003-4293-4461)
- Alberto Noto (ORCID: https://orcid.org/0000-0002-1490-9317)
- Santi Nolasco (ORCID: https://orcid.org/0000-0003-3995-7662)
- Federica Massaro
- Giuseppe Valenti (ORCID: https://orcid.org/0000-0002-2512-9017)
- Massimo Triggiani (ORCID: https://orcid.org/0000-0001-7318-2093)
- Vitaliano Nicola Quaranta (ORCID: https://orcid.org/0000-0001-9920-780X)
- Angelantonio Maglio (ORCID: https://orcid.org/0000-0003-1874-1686)
- Giovanna Elisiana Carpagnano (ORCID: https://orcid.org/0000-0001-7931-4704)
- Danilo Di Bona (ORCID: https://orcid.org/0000-0002-9728-3806)
- Silvano Dragonieri (ORCID: https://orcid.org/0000-0003-1563-6864)
- Elena Minenna
- Francesco Papia (ORCID: https://orcid.org/0000-0002-9544-8718)
- Alessandro Vatrella (ORCID: https://orcid.org/0000-0001-8265-3037)
- Luigi Macchia (ORCID: https://orcid.org/0000-0002-5896-086X)
- Lorena Gallotti
Institutions
- University of Foggia (IT)
- University of Messina (IT)
- University of Salerno (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- Marconi University (IT)
- Magna Graecia University (IT)
- University of Catania (IT)
- Neuroscience Institute (IT)
- Istituto Ortopedico Gaetano Pini (IT)
- Policlinico Universitario di Catania (IT)
- University of Bari Aldo Moro (IT)
- University of Naples Federico II (IT)
- University of Palermo (IT)
Publication Details
- Journal
- The Journal of Allergy and Clinical Immunology In Practice
- Published
- 2024-08-26
- DOI
- https://doi.org/10.1016/j.jaip.2024.08.033
- Citations
- 33
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 10.78
Funders
- AstraZeneca
- Sanofi
- Università degli Studi di Napoli Federico II
- McMaster University
- ResMed
- Università di Catania
- Università degli Studi di Palermo
- Università degli Studi di Salerno
- Università degli Studi di Messina