ART26.12, a novel fatty acid‐binding protein 5 inhibitor, shows efficacy in multiple preclinical neuropathy models

This work now shows that ART26.12, a novel and selective inhibitor of FABP5, can prevent and treat multiple preclinical models of peripheral neuropathy. Given its excellent safety profile, further work is warranted to develop ART26.12 as a potential therapeutic tool for pain management.

Authors

Publication Details

Journal
European Journal of Pain
Published
2024-08-26
DOI
https://doi.org/10.1002/ejp.4718
Citations
3
Primary Topic
Peroxisome Proliferator-Activated Receptors
Type
article
Field-Weighted Citation Impact
0.70
Controls
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article

ART26.12, a novel fatty acid‐binding protein 5 inhibitor, shows efficacy in multiple preclinical neuropathy models

W. G. Warren, Wenwen Xue, Ana David-Pereira, Saoirse E. O’Sullivan et al.
3 citations
European Journal of Pain
Peroxisome Proliferator-Activated Receptors
0.70
article

ART26.12, a novel fatty acid‐binding protein 5 inhibitor, shows efficacy in multiple preclinical neuropathy models

W. G. Warren, Wenwen Xue, Ana David-Pereira, Saoirse E. O’Sullivan, Andrew Yates, Christoforos Tsantoulas, Mary Osborn
article en
3 citations

Abstract

This work now shows that ART26.12, a novel and selective inhibitor of FABP5, can prevent and treat multiple preclinical models of peripheral neuropathy. Given its excellent safety profile, further work is warranted to develop ART26.12 as a potential therapeutic tool for pain management.

European Journal of PainVol. 29(2)
Good health and well-being
Openalex Percentile: Top 30%
Peroxisome Proliferator-Activated Receptors
0.70
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