Skin cancer risk in patients with BRCA mutations

Skin cancer risk in patients with BRCA mutationsTo the Editor: Patients with germline BReast CAncer gene (BRCA) mutations have a well-documented risk of cancers, such as breast, ovarian, prostate, and pancreatic. 1 Studies evaluating the association between BRCA mutations and skin cancer risk report inconsistent results and are limited by surveillance bias. 2 AK, Actinic keratosis; BRCA, BReast CAncer gene.*Listed are the number of patients who had at least one of each skin cancer type.y All keratinocyte carcinomas include BCC (basal cell carcinoma) and SCC (squamous cell carcinoma).