Violaceous nodules of the extensor joints – a clinicopathological challenge

Antineutrophilic cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a condition characterized by vessel inflammation and may have a variety of etiologies. Among these, cocaine and its common adulterant, levamisole, have been described to contribute to the development of AAV with distinct cutaneous manifestations. Classically, these manifestations involve purpuric or necrotic lesions involving the ears, nose, and extremities. However, we present a case of cocaine-induced AAV presenting with violaceous nodules on the dorsal hands in order to demonstrate that this condition may not always present with retiform purpura and skin necrosis.

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Publication Details

Journal
International Journal of Dermatology
Published
2024-08-26
DOI
https://doi.org/10.1111/ijd.17447
Citations
1
Primary Topic
Blood disorders and treatments
Type
article
Field-Weighted Citation Impact
0.55
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article

Violaceous nodules of the extensor joints – a clinicopathological challenge

Bijal Amin, Donald Lei, Michael A. Occidental, Jeanie Lee et al.
1 citations
International Journal of Dermatology
Blood disorders and treatments
0.55
article

Violaceous nodules of the extensor joints – a clinicopathological challenge

Bijal Amin, Donald Lei, Michael A. Occidental, Jeanie Lee, Benedict Wu, Daniel R. Antohi, Shudan Wang
article en
1 citations

Abstract

Antineutrophilic cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a condition characterized by vessel inflammation and may have a variety of etiologies. Among these, cocaine and its common adulterant, levamisole, have been described to contribute to the development of AAV with distinct cutaneous manifestations. Classically, these manifestations involve purpuric or necrotic lesions involving the ears, nose, and extremities. However, we present a case of cocaine-induced AAV presenting with violaceous nodules on the dorsal hands in order to demonstrate that this condition may not always present with retiform purpura and skin necrosis.

International Journal of DermatologyVol. 64(1)
Albert Einstein College of Medicine (US), Montefiore Medical Center (US)
Good health and well-being
Openalex Percentile: Top 26%
Blood disorders and treatments
0.55
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