Comparison of cytotoxicity methods for studying Vipera ammodytes venom and the anticytotoxic potency of antivenom
We concluded that the choice of the method used to measure the anticytotoxic anti-venom potency depends on the immunogenicity of the venom components that cause cell death; for each venom/antivenom pair, it is necessary to select the appropriate assay separately, and at present, none of the standard cytotoxic methods can be universally applied to determine antivenom potency.
Authors
- Saša Ivanović (ORCID: https://orcid.org/0000-0001-7134-4677)
- Ivana Lukić (ORCID: https://orcid.org/0000-0002-6330-471X)
- Sunčica Borozan (ORCID: https://orcid.org/0000-0002-6404-397X)
- Rajna Minić (ORCID: https://orcid.org/0000-0003-2941-9246)
- Veljko Blagojević (ORCID: https://orcid.org/0000-0002-8491-9924)
- Irena Živković (ORCID: https://orcid.org/0000-0002-4074-590X)
- Vitomir Ćupić (ORCID: https://orcid.org/0009-0001-0790-020X)
Institutions
- University of Belgrade (RS)
- Institute of Virology, Vaccines and Sera “Torlak” (RS)
Publication Details
- Journal
- Central European Journal of Immunology
- Published
- 2024-08-26
- DOI
- https://doi.org/10.5114/ceji.2024.142417
- Citations
- 3
- Primary Topic
- Venomous Animal Envenomation and Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.65
Funders
- Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja