Hepatic Visualization on DXA Scan: An Ancilliary Finding

Thalassemia major is a genetic haemoglobinopathy manifesting as severe anaemia, jaundice and hepatosplenomegaly. Due to altered iron metabolism and increased bone resorption it is associated with secondary osteoporosis manifested as decreased bone mineral density (BMD). Dual energy X-ray absorptiometry (DXA) is frequently performed for the diagnosis of secondary osteoporosis. Soft tissues are rarely visualized on DXA unless there is calcification involving those structures like nephro-, cholelithiasis or iatrogenic e.g. surgical clips. Hepatic iron deposition occurs in thalassemia due to repeated blood transfusions which leads to increased density of the liver resulting in visualization of liver on DXA scan. We present an interesting image of hepatic visualization on DXA performed for bone mineral density assessment in a patient with thalassemia major.

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Journal
Journal of the Pakistan Medical Association
Published
2024-08-23
DOI
https://doi.org/10.47391/jpma.24-73
Primary Topic
Machine Learning in Healthcare
Type
article
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article

Hepatic Visualization on DXA Scan: An Ancilliary Finding

Sana Munir Gill, Aamna Hassan, Ayesha Zubair
Journal of the Pakistan Medical Association
Machine Learning in Healthcare
article

Hepatic Visualization on DXA Scan: An Ancilliary Finding

Sana Munir Gill, Aamna Hassan, Ayesha Zubair
article en

Abstract

Thalassemia major is a genetic haemoglobinopathy manifesting as severe anaemia, jaundice and hepatosplenomegaly. Due to altered iron metabolism and increased bone resorption it is associated with secondary osteoporosis manifested as decreased bone mineral density (BMD). Dual energy X-ray absorptiometry (DXA) is frequently performed for the diagnosis of secondary osteoporosis. Soft tissues are rarely visualized on DXA unless there is calcification involving those structures like nephro-, cholelithiasis or iatrogenic e.g. surgical clips. Hepatic iron deposition occurs in thalassemia due to repeated blood transfusions which leads to increased density of the liver resulting in visualization of liver on DXA scan. We present an interesting image of hepatic visualization on DXA performed for bone mineral density assessment in a patient with thalassemia major.

Journal of the Pakistan Medical AssociationVol. 74(9)
Shaukat Khanum Memorial Cancer Hospital and Research Center (PK)
Openalex Percentile: Top 88%
Machine Learning in Healthcare
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Hepatic Visualization on DXA Scan: An Ancilliary Finding — Sana Munir Gill, Aamna Hassan, et al. · Journal of the Pakistan Medical Association (2024) | TGRS Research Map | TGRS