Animal amino acid sensor — A review
Cell growth and metabolism necessitate the involvement of amino acids, which are sensed and integrated by the mammalian target of rapamycin complex 1 (mTORC1). However, the molecular mechanisms underlying amino acid sensing remain poorly understood. Research indicates that amino acids are detected by specific sensors, with the signals being relayed to mTORC1 indirectly. This paper reviews the structures and biological functions of the amino acid sensors identified thus far. Additionally, it evaluates the potential role these sensors play in the developmental changes of the livestock production.
Authors
- Yongding Ke
- Xinyu Peng (ORCID: https://orcid.org/0000-0002-2692-9526)
- Xingtang Fang (ORCID: https://orcid.org/0000-0002-4013-9950)
- Yanhong Wang (ORCID: https://orcid.org/0009-0009-1647-5581)
- Chunlei Zhang (ORCID: https://orcid.org/0000-0002-0939-2149)
- Chengchuang Song
Institutions
- Jiangsu Normal University (CN)
- Jiangsu Second Normal University (CN)
Publication Details
- Journal
- Animal Bioscience
- Published
- 2024-08-26
- DOI
- https://doi.org/10.5713/ab.24.0366
- Citations
- 1
- Primary Topic
- Biopolymer Synthesis and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- National Natural Science Foundation of China
- Priority Academic Program Development of Jiangsu Higher Education Institutions