A Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Syndrome Manifestation in Tubercular Cervical Lymphadenopathy: A Case Report

A severe adverse reaction linked to a variety of medications, Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is typified by a severe mucocutaneous rash, eosinophilia, fever, lymphadenopathy, and widespread systemic involvement. A 30-year-old female patient presented with fever, facial flushing, and a maculopapular rash that had been persistent for seven days on the upper limb, chest, belly, and lower limbs. She also had a cough with breathlessness for seven days which had progressed over the last seven days and also a rise in temperature in the evening. As the patient was started on anti-tubercular treatment (ATT) based on an interferon-gamma release assay report with no constitutional symptoms, we decided to reconfirm the diagnosis. Ultrasonography of the neck showed cervical lymphadenopathy measuring 21x11 mm in the left cervical region at level IB. The patient was advised for cervical lymph node fine needle aspiration to be sent for cytology and cartridge-based nucleic acid amplification test (CBNAAT) to restart ATT. The patient is being followed up.