Ferric carboxymaltose and exercise capacity in heart failure with preserved ejection fraction and iron deficiency: the FAIR-HFpEF trial
In patients with HFpEF and markers of ID, intravenous FCM improved 6MWTD and was associated with fewer serious adverse events. However, the trial lacked sufficient power to identify or refute effects on symptoms or QoL. The potential benefits of intravenous iron in HFpEF with ID should be investigated further in a larger cohort.
Authors
- Stefan D. Anker (ORCID: https://orcid.org/0000-0002-0805-8683)
- Michael Böhm (ORCID: https://orcid.org/0000-0002-2976-2514)
- Piotr Ponikowski (ORCID: https://orcid.org/0000-0002-3391-7064)
- Javed Butler (ORCID: https://orcid.org/0000-0001-7683-4720)
- Stephan von Haehling (ORCID: https://orcid.org/0000-0002-9818-042X)
- Tania Garfias‐Veitl (ORCID: https://orcid.org/0000-0003-3672-4046)
- Tim Friede (ORCID: https://orcid.org/0000-0001-5347-7441)
- Mitja Lainščak (ORCID: https://orcid.org/0000-0002-5922-4098)
- Monika Diek
- Ralf Birkemeyer
- Wolfram Doehner (ORCID: https://orcid.org/0000-0001-7598-708X)
- Mahir Karakas (ORCID: https://orcid.org/0000-0002-5715-2959)
- Ruben Evertz (ORCID: https://orcid.org/0000-0002-5904-4652)
- Carlotta Derad (ORCID: https://orcid.org/0000-0001-9542-4647)
- Gerasimos Fillippatos
Institutions
- University of Ljubljana (SI)
- Universität Hamburg (DE)
- National and Kapodistrian University of Athens (GR)
- Jackson Memorial Hospital (US)
- University of Mississippi Medical Center (US)
- Wroclaw Medical University (PL)
- Pomurski muzej Murska Sobota (SI)
- Universitätsklinikum des Saarlandes (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- Baylor Medical Center at Garland (US)
- Universitätsmedizin Göttingen (DE)
- German Centre for Cardiovascular Research (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- University Hospital Ulm (DE)
- University of Göttingen (DE)
- Charité - Universitätsmedizin Berlin (DE)
- Saarland University (DE)
Publication Details
- Journal
- European Heart Journal
- Published
- 2024-08-26
- DOI
- https://doi.org/10.1093/eurheartj/ehae479
- Citations
- 66
- Primary Topic
- Erythropoietin and Anemia Treatment
- Type
- article
- Field-Weighted Citation Impact
- 29.99
Funders
- Vifor Pharma