High-level ceftriaxone resistance due to transfer of <i>penA</i> allele 60.001 into endemic gonococcal lineages in Hangzhou, China
Here, we report continued transmission of gonococcal strains associated with the FC428 clone or containing penA allele 60.001 in Hangzhou. A major concern for public health is the acquisition of penA allele 60.001 by successful endemic lineages, which might enhance the transmission of this high-level ceftriaxone resistance trait.
Authors
- Yan Chen (ORCID: https://orcid.org/0000-0002-7679-1713)
- Xiao Wei Sun (ORCID: https://orcid.org/0000-0002-2840-1880)
- Ying Fu (ORCID: https://orcid.org/0000-0003-1177-0871)
- Stijn van der Veen (ORCID: https://orcid.org/0000-0002-8176-391X)
- Xu’ai Lin
- Feng Zhao (ORCID: https://orcid.org/0000-0003-0850-9357)
- Fan Yang (ORCID: https://orcid.org/0000-0002-8111-4880)
Institutions
- Sir Run Run Shaw Hospital (CN)
- Zhejiang University-University of Edinburgh Institute (CN)
- First Affiliated Hospital Zhejiang University (CN)
- State Key Laboratory of Diagnosis and Treatment of Infectious Diseases
- Zhejiang University (CN)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2024-08-26
- DOI
- https://doi.org/10.1093/jac/dkae297
- Citations
- 9
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 3.10
Funders
- National Natural Science Foundation of China