<i>Helicobacter pylori</i> Eradication Therapy for Colorectal Mucosa-associated Lymphoid Tissue Lymphoma: Report of Two Cases.

Two cases of colorectal mucosa-associated lymphoid tissue lymphoma (cMALT) are presented and discussed with the reports from 1997 to the present. Helicobacter pylori (<i>HP</i>)-negative cases showed tumor resolution 2 months after eradication therapy. <i>HP</i>-positive cases were successfully eradicated and tumor resolution was confirmed 16 months later. Analysis of the data reported to date shows that cMALT resolution rates were 68.4% (13/19) in the <i>HP</i>-negative group and 33.3% (7/21) in the <i>HP</i>-positive group. <i>HP</i> eradication should be considered the primary treatment for cMALT regardless of <i>HP</i> infection, especially in untreated patients under follow-up.