Genetic liability to human serum metabolites is causally linked to telomere length: insights from genome-wide Mendelian randomization and metabolic pathways analysis
Our MR analysis provided suggestive evidence supporting the causal relationships between 11 identified blood metabolites and TL, necessitating further exploration to clarify the mechanisms by which these serum metabolites and metabolic pathways may affect the progression of telomeres.
Authors
- Renbing Pan (ORCID: https://orcid.org/0000-0001-9627-568X)
- Jingwen Liu (ORCID: https://orcid.org/0000-0002-9825-9760)
Institutions
- Wenzhou Medical University (CN)
- Sir Run Run Shaw Hospital (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2024-08-26
- DOI
- https://doi.org/10.3389/fnut.2024.1458442
- Citations
- 1
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 0.33