shRNA-interfered of Nrf2 reveals a critical role for Keap1-Nrf2 signaling pathway during effects of zearalenone induced oxidative stress in IPEC-J2 cells
These results further prove that interfering with the expression of Nrf2 in IPEC-J2 cells affected the activation of the Keap1-Nrf2 signaling pathway and reduced the ability of cells to resist ZEA-induced oxidative stress. Therefore, the Keap1-Nrf2 signaling pathway had an important protective effect in ZEA-induced intestinal oxidative stress.
Authors
- Qun Cheng (ORCID: https://orcid.org/0000-0001-5988-446X)
- Wei Yang (ORCID: https://orcid.org/0000-0002-4709-0555)
- Li bo Huang
- Shu zhen Jiang
Institutions
- Qingdao Agricultural University (CN)
- Shandong Agricultural University (CN)
Publication Details
- Journal
- Animal Bioscience
- Published
- 2024-08-26
- DOI
- https://doi.org/10.5713/ab.24.0368
- Citations
- 1
- Primary Topic
- Genomics, phytochemicals, and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- Qingdao Agricultural University
- Natural Science Foundation of Shandong Province
- Shandong Agriculture Research System