Exploring the utility of ultrasound to assess disuse atrophy in different muscles of the lower leg
Both MT<sub>U/S</sub> and CSA<sub>U/S</sub> provide comparable static measures of lower leg muscle size compared with MRI, albeit with weaker agreement in TA compared to MG. Although both MT<sub>U/S</sub> and CSA<sub>U/S</sub> can discern differences in DMA susceptibility between muscles, neither can reliably assess degree of DMA. Based on the growing recognition of heterogeneous atrophy profiles between muscles, and the topical importance of less commonly studied muscles (i.e., TA for falls prevention in older adults), future research should aim to optimize accessible methods to determine muscle losses across the body.
Authors
- Jonathan N. Lund (ORCID: https://orcid.org/0000-0001-5195-2181)
- Jessica Piasecki (ORCID: https://orcid.org/0000-0001-9758-6295)
- Bethan E. Phillips (ORCID: https://orcid.org/0000-0002-1430-1870)
- Philip J. Atherton (ORCID: https://orcid.org/0000-0002-7286-046X)
- Daniel J. Wilkinson (ORCID: https://orcid.org/0000-0001-8808-8243)
- Ken R. Smith (ORCID: https://orcid.org/0000-0003-0682-3705)
- Joseph J. Bass
- Edward Hardy
- Thomas B. Inns (ORCID: https://orcid.org/0000-0002-9876-4468)
- Craig Sale (ORCID: https://orcid.org/0000-0002-5816-4169)
- R.H. Morris (ORCID: https://orcid.org/0000-0001-5511-3457)
- Mathew Piasecki (ORCID: https://orcid.org/0000-0002-7804-4631)
Institutions
- Manchester Metropolitan University (GB)
- University of Nottingham (GB)
- Royal Derby Hospital (GB)
- Arthritis UK (GB)
- Nottingham Trent University (GB)
Publication Details
- Journal
- Journal of Cachexia Sarcopenia and Muscle
- Published
- 2024-08-26
- DOI
- https://doi.org/10.1002/jcsm.13583
- Citations
- 3
- Primary Topic
- Sports injuries and prevention
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- National Institute for Health and Care Research
- Versus Arthritis
- Medical Research Council
- Biotechnology and Biological Sciences Research Council
- NIHR Nottingham Biomedical Research Centre