Causal associations of obstructive sleep apnea with Chronic Respiratory Diseases: a Mendelian Randomization study
Our findings reveal a BMI-mediated protective effect of OSA on COPD, with no causal connections identified between OSA and other CRDs. These results emphasize the complex relationship between OSA, BMI, and COPD, guiding future clinical strategies and research directions, particularly in light of the study's genetic analysis limitations.
Authors
- Yiming Zeng (ORCID: https://orcid.org/0000-0001-6429-0682)
- Ping-Yang Hong
- Xiaobin Zhang (ORCID: https://orcid.org/0000-0002-0577-5951)
- Ang Liu (ORCID: https://orcid.org/0000-0001-9353-0948)
- Dong Liu
- Xin Su
Institutions
- Fujian Medical University (CN)
- Xiamen University (CN)
- Shantou University (CN)
- Zhongshan Hospital of Xiamen University (CN)
- Second Affiliated Hospital of Fujian Medical University (CN)
- Heze Municipal Hospital (CN)
Publication Details
- Journal
- BMC Pulmonary Medicine
- Published
- 2024-08-26
- DOI
- https://doi.org/10.1186/s12890-024-03228-x
- Citations
- 4
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 1.31
Funders
- National Natural Science Foundation of China
- Fujian Provincial Health Technology Project