Altered individual-level morphological similarity network in children with growth hormone deficiency
GHD undergo an extensive reorganization in large-scale individual-level MBNs, probably due to abnormal cortico-striatal-thalamo-cerebellum loops, cortico-limbic-cerebellum, dorsal visual-sensorimotor-striatal, and auditory-cerebellum circuitry. This study highlights the crucial role of abnormal morphological connectivity underlying GHD, which might result in their relatively slower development in motor, cognitive, and linguistic functional within behavior problem performance.
Authors
- Yanglei Cheng
- Zhiyun Yang (ORCID: https://orcid.org/0000-0002-6139-9049)
- Qiuli Chen (ORCID: https://orcid.org/0009-0002-0657-6222)
- Zi Yan (ORCID: https://orcid.org/0000-0001-8188-5549)
- Long Qian (ORCID: https://orcid.org/0000-0002-9707-1096)
- Yanbing Li (ORCID: https://orcid.org/0000-0003-3782-9210)
- Wei Cui (ORCID: https://orcid.org/0000-0002-2049-0508)
- Huaqiong Qiu
- Shu Su (ORCID: https://orcid.org/0000-0001-8704-9752)
- Liping Lin
- Weifeng Hou
- Chengfen Deng
Institutions
- Sun Yat-sen University (CN)
- Peking University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Journal of Neurodevelopmental Disorders
- Published
- 2024-08-26
- DOI
- https://doi.org/10.1186/s11689-024-09566-5
- Citations
- 2
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Basic and Applied Basic Research Foundation of Guangdong Province